Research & Clinical trials

A tech-enabled adherence solution designed for patients and study teams

Our flexible, asynchronous, video technology & review service allows for dose-by-dose insights to help
sponsors and CROs accelerate trials.

Increase
Adherence

With asynchronous video technology and service, every dose is directly observed, improving data accuracy and adherence. Real-time data ensures compliance is tracked earlier and more effectively, helping teams take corrective action when needed. This results in better efficacy estimates and enhanced patient support.

Improve Retention

Scene’s patient-centric design, low-tech requirements, and availability in multiple languages reduces barriers to trial participation. Early dose-by-dose identification of potential adherence issues enables rapid, patient-specific interventions that support each patient through their clinical study journey, reducing study dropout and, thus, improving retention.

Boost Efficiency

Scene offers white-glove support to ensure smooth execution and high-quality data while speeding up trial completion. Our flexible approach accommodates various study protocols and administration methods—whether orals, inhalers, topicals, or injections. Scene delivers reliable, on-time, and cost-effective trial completion without adding an unnecessary burden on the sites.

Frictionless onboarding & reporting
streamlines operations for study teams

Patient App

Patients complete video check-ins of each dose, anytime and anywhere using our easy-to-use app. The Scene adherence team visually confirms that every dose of medication is ingested properly using our patented review portal. Scene’s adherence platform offers:

  • Configurable medication reminders
  • Low-tech requirements (BYOD)
  • In-app messaging
  • Over 20 languages
  • Time and date-stamped video submissions
  • Livestream video appointments
Customized Adherence
Review Service

Scene's review, engagement, escalation is configured in a playbook, based on trial-specific protocols. Reviewers to assess videos and alert stakeholders to potential issues. This timely escalation and engagement helps ensure better patient adherence and engagement management.

  • Dose-by-dose medication assessment
  • Customizable medication reminders
  • Secure 2-way chat & video messaging
  • Side effects and symptoms reporting
  • Asynch & livestream video appointments
  • Adherence tracking
Real-time Analytics

Detailed patient, site, and population-level analytics are available on demand via configurable dashboards. Accurate dosing data lets sponsors and CROs know which patients are at risk of missing adherence targets and provides a view into which study sites need additional support enabling early interventions.

  • Data review with dedicated Project Manager
  • Real-time adherence analytics
  • Time and date-stamped dosing
  • Adherence trends per site
  • Dosing trends
  • Separate sponsor and study team dashboards

Phase II Clinical Trial Treatment for Major Depressive Disorder

97.4%
Adherence to daily treatment at home (1x/day) for 28 days.

129 patients across 32 US sites.
89.2%
of patients in treatment phase completed.

Only 11% drop out rate (Typical rates 30-50%)
Scene's adherence solution was pivotal for the Phase II trial of esketamine for Major Depressive Disorder patients unresponsive to standard therapies. By leveraging Scene's tech-enabled service the Sponsor ensured high medication adherence and accurate dosing in a population known to struggle with adherence rates below 50%.
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25 peer-reviewed publications across diverse populations & indications

Our technology-enabled service is validated across diverse populations and indications, with publications reporting up to 98% adherence in underrepresented, high-cost patient groups in both clinical and real-world settings.

Scene integrated seamlessly into our protocol and provided valuable insights into the overall status of our trial.”

Clinical Trial Manager, Sponsor

Scene improved the efficiency of our trial without placing extra burden on participants or trial sites.”

Clinical Trial Manager, Sponsor

Scene integrated seamlessly into our protocol and provided valuable insights into the overall status of our trial.”

Sr. Director, 
Clinical Trial Management, CRO

Partnering with thought leaders across the healthcare landscape to radically improve medication adherence.